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  Genetic diversity of HLA system in two populations from Tamaulipas, Mexico: Ciudad Victoria and rural Tamaulipas

Rodríguez-Munguía, T. J., Barquera, R., Adalid-Sáinz, C., Hernández-Zaragoza, D. I., Arrieta-Bolaños, E., Clayton, S., et al. (2019). Genetic diversity of HLA system in two populations from Tamaulipas, Mexico: Ciudad Victoria and rural Tamaulipas. Human Immunology. doi:10.1016/j.humimm.2019.07.288.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0004-59D3-A Version Permalink: http://hdl.handle.net/21.11116/0000-0004-59D4-9
Genre: Journal Article

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 Creators:
Rodríguez-Munguía, Tirzo Jesús, Author
Barquera, Rodrigo1, Author              
Adalid-Sáinz, Carmen, Author
Hernández-Zaragoza, Diana Iraíz, Author
Arrieta-Bolaños, Esteban, Author
Clayton, Stephen1, Author              
Aquino-Rubio, Guadalupe, Author
González-Martínez, Marisela del Rocío, Author
Pacheco-Ubaldo, Hanna, Author
González-Medina, Liliana, Author
Lona-Sánchez, Abraham, Author
Bravo-Acevedo, Alicia, Author
Delgado-Aguirre, Héctor, Author
Escareño-Montiel, Néstor, Author
Jaramillo-Rodríguez, Yolanda, Author
Salgado-Adame, Antonio, Author
la Cruz, Federico Juárez-de, Author
Zúñiga, Joaquín, Author
Yunis, Edmond J., Author
Bekker-Méndez, Carolina, Author
Granados, Julio, Author more..
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              

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Free keywords: HLA, Immunogenetics, Population genetics, Tamaulipas, Admixture
 Abstract: We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 148 Mexicans from the state of Tamaulipas living in Ciudad Victoria (N = 23) and rural communities (N = 125), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in the state of Tamaulipas include ten Native American, three European and one African haplotypes. Admixture estimates revealed that the main genetic components in the state of Tamaulipas are Native American (54.69 ± 0.93 by ML; 47.65 of Native American haplotypes) and European (34.66 ± 5.62 by ML; 33.56 of European haplotypes), and a relatively high African genetic component (10.65 ± 5.05 by ML; 12.42 of African haplotypes).

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Language(s): eng - English
 Dates: 2019-07-22
 Publication Status: Published online
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Method: Internal
 Identifiers: DOI: 10.1016/j.humimm.2019.07.288
Other: shh2310
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Title: Human Immunology
Source Genre: Journal
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Publ. Info: New York, N.Y. : Elsevier
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: ISSN: 0198-8859
CoNE: https://pure.mpg.de/cone/journals/resource/954925492912