English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Strain- or stress-sensing in mechanochemical patterning by the phytohormone auxin

Julien, J.-D., Pumir, A., & Boudaoud, A. (2019). Strain- or stress-sensing in mechanochemical patterning by the phytohormone auxin. Bulletin of Mathematical Biology, 81(8), 3342-3361. doi:10.1007/s11538-019-00600-5.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0004-94D6-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-94D7-2
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Julien, Jean-Daniel1, Author              
Pumir, Alain2, Author              
Boudaoud, A., Author
Affiliations:
1Max Planck Research Group Biological Physics and Morphogenesis, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2266692              
2Laboratory for Fluid Dynamics, Pattern Formation and Biocomplexity, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063287              

Content

show
hide
Free keywords: Patterning; Chemomechanical model; Auxin transport; Shoot apical meristem
 Abstract: Both chemical and mechanical fields are known to play a major role in morphogenesis. In plants, the phytohormone auxin and its directional transport are essential for the formation of robust patterns of organs, such as flowers or leaves, known as phyllotactic patterns. The transport of auxin was recently shown to be affected by mechanical signals, and conversely, auxin accumulation in incipient organs affects the mechanical properties of the cells. The precise interaction between mechanical fields and auxin transport, however, is poorly understood. In particular, it is unknown whether transport is sensitive to the strain or to the stress exerted on a given cell. Here, we investigate the nature of this coupling with the help of theoretical models. Namely, we introduce the effects of either mechanical stress or mechanical strain in a model of auxin transport and compare the patterns predicted with available experimental results, in which the tissue is perturbed by ablations, chemical treatments, or genetic manipulations. We also study the robustness of the patterning mechanism to noise and investigate the effect of a shock that changes abruptly its parameters. Although the model predictions with the two different feedbacks are often indistinguishable, the strain feedback seems to better agree with some of the experiments. The computational modeling approach used here, which enables us to distinguish between several possible mechanical feedbacks, offers promising perspectives to elucidate the role of mechanics in tissue development, and may help providing insight into the underlying molecular mechanisms.

Details

show
hide
Language(s): eng - English
 Dates: 2019-03-222019-08
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1007/s11538-019-00600-5
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Bulletin of Mathematical Biology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 81 (8) Sequence Number: - Start / End Page: 3342 - 3361 Identifier: -