English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mapping complementary features of cross-species structural connectivity to construct realistic “virtual brains”

Bezgin, G., Solodkin, A., Bakker, R., Ritter, P., & McIntosh, A. R. (2017). Mapping complementary features of cross-species structural connectivity to construct realistic “virtual brains”. Human Brain Mapping, 38(4), 2080-2093. doi:10.1002/hbm.23506.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0004-A979-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-DCAB-4
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Bezgin, Gleb1, 2, Author
Solodkin, Ana3, Author
Bakker, Rembrandt4, 5, Author
Ritter, Petra6, 7, 8, 9, Author              
McIntosh, Anthony R.1, 10, Author
Affiliations:
1Baycrest Health Sciences, Rotman Research Institute, University of Toronto, ON, Canada, ou_persistent22              
2McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada, ou_persistent22              
3Department of Neurology, University of California, Irvine, CA, USA, ou_persistent22              
4Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands, ou_persistent22              
5Institute of Neuroscience and Medicine, Research Center Jülich, Germany, ou_persistent22              
6Department of Neurology, Charité University Medicine Berlin, Germany, ou_persistent22              
7Minerva Research Group Brain Modes, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_751546              
8Bernstein Center for Computational Neuroscience, Berlin, Germany, ou_persistent22              
9Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              
10Department of Psychology, University of Toronto, ON, Canada, ou_persistent22              

Content

show
hide
Free keywords: Bayesian modeling; The Virtual Brain; Cerebral cortex; Connectivity; Diffusion tensor imaging; Neuroanatomy; Primate brain; Subcortex; Tract tracing
 Abstract: Modern systems neuroscience increasingly leans on large-scale multi-lab neuroinformatics initiatives to provide necessary capacity for biologically realistic modeling of primate whole-brain activity. Here, we present a framework to assemble primate brain's biologically plausible anatomical backbone for such modeling initiatives. In this framework, structural connectivity is determined by adding complementary information from invasive macaque axonal tract tracing and non-invasive human diffusion tensor imaging. Both modalities are combined by means of available interspecies registration tools and a newly developed Bayesian probabilistic modeling approach to extract common connectivity evidence. We demonstrate how this novel framework is embedded in the whole-brain simulation platform called The Virtual Brain.

Details

show
hide
Language(s): eng - English
 Dates: 2016-11-082015-09-142016-12-202017-01-052017-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/hbm.23506
PMID: 28054725
Other: Epub 2017
 Degree: -

Event

show

Legal Case

show

Project information

show hide
Project name : -
Grant ID : 220020255
Funding program : -
Funding organization : JS McDonnell Collaborative Research
Project name : -
Grant ID : BC_Azrieli_MIRI_3388
Funding program : -
Funding organization : Azrieli Foundation
Project name : -
Grant ID : 01GQ0801
Funding program : -
Funding organization : German Federal Ministry of Education and Research (BMBF)
Project name : -
Grant ID : -
Funding program : -
Funding organization : Helmholtz Association HASB and Portfolio Theme SMHB
Project name : Brain-inspired multiscale computation in neuromorphic hybrid systems / BRAINSCALES
Grant ID : 269921
Funding program : Funding Programme 7
Funding organization : European Commission (EC)
Project name : Bernstein Focus State Dependencies of Learning
Grant ID : 01GQ0971
Funding program : -
Funding organization : German Federal Ministry of Education and Research (BMBF)
Project name : US-German Collaboration in Computational Neuroscience
Grant ID : 01GQ1504A
Funding program : -
Funding organization : German Federal Ministry of Education and Research (BMBF)
Project name : -
Grant ID : -
Funding program : -
Funding organization : Max‐Planck Society
Project name : Personalized whole brain simulations: linking connectomics and dynamics in the human brain / BrainModes
Grant ID : 683049
Funding program : Horizon 2020
Funding organization : European Commission (EC)

Source 1

show
hide
Title: Human Brain Mapping
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 38 (4) Sequence Number: - Start / End Page: 2080 - 2093 Identifier: ISSN: 1065-9471
CoNE: https://pure.mpg.de/cone/journals/resource/954925601686