English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Development of a novel instrument to measure the pulsatile movement of ocular tissues

Singh, K., Dion, C., Costantino, S., Wajszilber, M., Lesk, M. R., & Ozaki, T. (2010). Development of a novel instrument to measure the pulsatile movement of ocular tissues. EXPERIMENTAL EYE RESEARCH, 91(1), 63-68. doi:10.1016/j.exer.2010.03.022.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Singh, Kanwarpal1, Author              
Dion, C.2, Author
Costantino, S.2, Author
Wajszilber, M.2, Author
Lesk, M. R.2, Author
Ozaki, T.2, Author
Affiliations:
1External Organizations, ou_persistent22              
2external, ou_persistent22              

Content

show
hide
Free keywords: low-coherence interferometry; eye kinematics; longitudinal movement;
 Abstract: We demonstrate an optical instrument that can measure the axial displacement of different eye tissues, including the cornea and the fundus. The instrument is based on spectral-domain low-coherence interferometry, which extracts displacement information from sequential axial scans of the eye with 100 Hz sampling frequency and with a precision of 400 nm. Longitudinal retinal and corneal movements were successfully measured in vivo in live rats, and Fourier analysis of the signal revealed the signature of the respiratory and cardiac cycles at 1.0 and 3.5 Hz, respectively. The effective amplitudes of retinal and corneal displacements at the cardiac frequency were found to be about 1.10 and 1.37 mu m, respectively. The synchrony and direction of these two movements relative to the systole and diastole were found to be nearly the same. This novel instrument can be applied to assess biomechanical properties of the eye, which could be important for early diagnosis and for understanding the pathophysiology of glaucoma and other ocular diseases. (C) 2010 Elsevier Ltd. All rights reserved.

Details

show
hide
Language(s): eng - English
 Dates: 2010-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.exer.2010.03.022
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: EXPERIMENTAL EYE RESEARCH
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND : ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Pages: - Volume / Issue: 91 (1) Sequence Number: - Start / End Page: 63 - 68 Identifier: ISSN: 0014-4835