English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The binding of iron to perineuronal nets: A combined nuclear microscopy and Mössbauer study

Morawski, M., Reinert, T., Brückner, G., Wagner, F., Arendt, T., & Tröger, W. (2004). The binding of iron to perineuronal nets: A combined nuclear microscopy and Mössbauer study. Hyperfine Interactions, 159(1-4), 285-291. doi:10.1007/3-540-30924-1_116.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0004-C6B7-E Version Permalink: http://hdl.handle.net/21.11116/0000-0004-C6B8-D
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Morawski, Markus1, Author              
Reinert, Tilo2, Author              
Brückner, G.1, Author
Wagner, F.3, Author
Arendt, T.1, Author
Tröger, W.2, Author
Affiliations:
1Paul Flechsig Institute für Hirnforschung, University of Leipzig, Germany, ou_persistent22              
2Fakultät für Physik und Geowissenschaften, University of Leipzig, Germany, ou_persistent22              
3Physic Department, TU Munich, Germany, ou_persistent22              

Content

show
hide
Free keywords: brain research; iron; life sciences; Mössbauer effect; particle induced X-ray emission; perineuronal nets
 Abstract: Abstractnbsp;nbsp;A specialized form of extracellular matrix (ECM) surrounds subpopulations of neurons termed `perineuronal nets' (PNs). These PNs form highly anionic charged structures in the direct microenvironment of neurons, assumed to be involved in local ion homeostasis since they are able to scavenge and bind redox--active iron ions. The quantity and distribution of iron--charged PNs of the extracellular matrix in the rat brain areas of the cortex and the red nucleus was investigated using the powerful combination of Particle--Induced X--ray Emission (PIXE) and M?ssbauer spectroscopy. These studies reveal that the iron is bound to the PNs as Fe(III). PNs in both brain regions accumulate up to three to five times more Fe3+ than any other tissue structure in dependency on the applied Fe concentration with local amount maximums of 480nbsp;mmol/l Fe at PNs.

Details

show
hide
Language(s): eng - English
 Dates: 2005-10-112004-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1007/3-540-30924-1_116
BibTex Citekey: Morawski:2004
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Hyperfine Interactions
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Basel, Switzerland [etc.] : J.C. Baltzer [etc.]
Pages: - Volume / Issue: 159 (1-4) Sequence Number: - Start / End Page: 285 - 291 Identifier: ISSN: 0304-3843
CoNE: https://pure.mpg.de/cone/journals/resource/954925511444