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  The architecture of cartilage: Elemental maps and scanning transmission ion microscopy/tomography

Reinert, T., Reibetanz, U., Sakellariou, A., Schwertner, M., Vogt, J., & Butz, T. (2002). The architecture of cartilage: Elemental maps and scanning transmission ion microscopy/tomography. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 188(1-4), 1-8. doi:10.1016/S0168-583X(01)01001-1.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0004-C56B-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-C571-E
Genre: Journal Article

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 Creators:
Reinert, Tilo1, Author              
Reibetanz, U.1, Author
Sakellariou, A.2, Author
Schwertner, M.1, Author
Vogt, J.1, Author
Butz, T.1, Author
Affiliations:
1Fakultät für Physik und Geowissenschaften, Nukleare Festkörperphysik, University of Leipzig, Germany, ou_persistent22              
2Research School Physical Sciences and Engineering Australian National University, Canberra, Australia, ou_persistent22              

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Free keywords: Cartilage; Collagen; Nuclear microscopy; Micro-PIXE; STIM tomography
 Abstract: Articular cartilage is not just a jelly-like cover of the bone within the joints but a highly sophisticated architecture of hydrated macromolecules, collagen fibrils and cartilage cells. Influences on the physiological balance due to age-related or pathological changes can lead to malfunction and subsequently to degradation of the cartilage. Many activities in cartilage research are dealing with the architecture of joint cartilage but have limited access to elemental distributions. Nuclear microscopy is able to yield spatially resolved elemental concentrations, provides density information and can visualise the arrangement of the collagen fibres. The distribution of the cartilage matrix can be deduced from the elemental and density maps. The findings showed a varying content of collagen and proteoglycan between zones of different cell maturation. Zones of higher collagen content are characterised by aligned collagen fibres that can form tubular structures. Recently we focused on STIM tomography to investigate the three dimensional arrangement of the collagen structures.

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Language(s): eng - English
 Dates: 2001-12-012002-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/S0168-583X(01)01001-1
BibTex Citekey: Reinert:2002
 Degree: -

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Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
  Abbreviation : NIM B
Source Genre: Journal
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Affiliations:
Publ. Info: Amsterdam : Elsevier B.V.
Pages: - Volume / Issue: 188 (1-4) Sequence Number: - Start / End Page: 1 - 8 Identifier: ISSN: 0168-583X
CoNE: https://pure.mpg.de/cone/journals/resource/954925484704