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  Quantifying the myelin and iron contents of the brain in vivo using a linear model of relaxation

Metere, R., & Möller, H. E. (2018). Quantifying the myelin and iron contents of the brain in vivo using a linear model of relaxation. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0004-C431-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-C432-6
Genre: Poster

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 Creators:
Metere, Riccardo1, Author              
Möller, Harald E.1, Author              
Affiliations:
1Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634558              

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 Abstract: Quantitative MRI maps are believed to strongly correlate with myelin and iron contents. Recently, a linear model combining prior information from non-MRI techniques was proposed for quantifying myelin and iron based on relaxometry (R1 and R2*) in post-mortem human brain samples. Here, we propose an adaptation of the linear relaxation model that is capable of predicting (with some limitations) the myelin and iron contents of the brain under in vivo conditions. It uses prior knowledge from the literature to calibrate the linear coefficients and was validated in a cohort of 10 subjects.

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 Dates: 2018-06-21
 Publication Status: Not specified
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
Start-/End Date: 2018-06-16 - 2018-06-21

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Title: Proceedings of the International Society for Magnetic Resonance in Medicine (2018)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 5505 Start / End Page: - Identifier: -