English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Pan-embryo cell dynamics of germlayer formation in zebrafish

Shah, G., Thierbach, K., Schmid, B., Reade, A., Roeder, I., Scherf, N., et al. (2017). Pan-embryo cell dynamics of germlayer formation in zebrafish. bioRxiv. doi:10.1101/173583.

Item is

Files

show Files
hide Files
:
Shah_2017.pdf (Preprint), 8MB
Name:
Shah_2017.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Shah, Gopi1, Author
Thierbach, Konstantin1, Author           
Schmid, Benjamin1, Author
Reade, Anna1, Author
Roeder, Ingo1, Author
Scherf, Nico1, Author           
Huisken, Jan1, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Cell movements are coordinated across spatio-temporal scales to achieve precise positioning of organs during vertebrate gastrulation. In zebrafish, mechanisms governing such morphogenetic movements have so far only been studied within a local region or a single germlayer. Here, we present pan-embryo analyses of fate specification and dynamics of all three germlayers simultaneously within a gastrulating embryo, showing that cell movement characteristics are predominantly determined by its position within the embryo, independent of its germlayer identity. The spatially confined fate specification establishes a distinct distribution of cells in each germlayer during early gastrulation. The differences in the initial distribution are subsequently amplified by a unique global movement, which organizes the organ precursors along the embryonic body axis, giving rise to the blueprint of organ formation.

Details

show
hide
Language(s): eng - English
 Dates: 2017-08-09
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: No review
 Identifiers: DOI: 10.1101/173583
BibTex Citekey: Shah173583
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: bioRxiv
Source Genre: Web Page
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: -