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  New Directions in C–H Fluorination

Cheng, Q., & Ritter, T. (2019). New Directions in C–H Fluorination. Trends in Chemistry, 1(5), 461-470. doi:10.1016/j.trechm.2019.04.001.

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Genre: Journal Article

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 Creators:
Cheng, Qiang1, Author              
Ritter, Tobias1, Author              
Affiliations:
1Research Department Ritter, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_2040308              

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Free keywords: C-H fluorination; fluoride; fluorinating reagent; late-stage fluorination; selectivity
 Abstract: One-step transformations from C–H to C–F are attractive methods especially if fluorine can be introduced at a late-stage of the synthesis. However, C–H fluorination is still an unsolved problem with just few successful approaches so far (as opposed to all other halogenation reactions). In this opinion, we highlight the challenges associated with C–H fluorination and discuss current progress for three different classes: directed fluorination, aliphatic fluorination, and aromatic fluorination.

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Language(s): eng - English
 Dates: 2019-01-232019-04-042019-05-082019-08-01
 Publication Status: Published in print
 Pages: 10
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.trechm.2019.04.001
 Degree: -

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Title: Trends in Chemistry
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier / CellPress
Pages: - Volume / Issue: 1 (5) Sequence Number: - Start / End Page: 461 - 470 Identifier: ISSN: 2589-5974
CoNE: https://pure.mpg.de/cone/journals/resource/2589-5974