English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Interspecific gene exchange introduces high genetic variability in crop pathogen

Feurtey, A., Stevens, D. M., Stephan, W., & Stukenbrock, E. H. (2019). Interspecific gene exchange introduces high genetic variability in crop pathogen. Genome Biology and Evolution, 11(11), 3095-3105. doi:10.1093/gbe/evz224.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0004-ED45-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-1D29-E
Genre: Journal Article

Files

show Files
hide Files
:
evz224.pdf (Any fulltext), 475KB
Name:
evz224.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Feurtey, Alice1, Author              
Stevens, Danielle M.1, Author              
Stephan, Wolfgang, Author
Stukenbrock, Eva H.1, Author              
Affiliations:
1Max Planck Fellow Group Environmental Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_2068284              

Content

show
hide
Free keywords: Interspecific hybridization, recurrent introgression, genome evolution, fungal pathogens
 Abstract: Genome analyses have revealed a profound role of hybridization and introgression in the evolution of many eukaryote lineages, including fungi. The impact of recurrent introgression on fungal evolution however remains elusive. Here, we analyzed signatures of introgression along the genome of the fungal wheat pathogen Zymoseptoria tritici. We applied a comparative population genomics approach, including genome data from five Zymoseptoria species, to characterize the distribution and composition of introgressed regions representing segments with an exceptional haplotype pattern. These regions are found throughout the genome, comprising five percent of the total genome and overlapping with > 1000 predicted genes. We performed window-based phylogenetic analyses along the genome to distinguish regions which have a monophyletic or non-monophyletic origin with Z. tritici sequences. A majority of non-monophyletic windows overlap with the highly variable regions suggesting that these originate from introgression. We verified that incongruent gene genealogies do not result from incomplete lineage sorting (ILS) by comparing the observed and expected length distribution of haplotype blocks resulting from ILS. Although protein-coding genes are not enriched in these regions, we identify 18 that encode putative virulence determinants. Moreover, we find an enrichment of transposable elements (TEs) in these regions implying that hybridization may contribute to the horizontal spread of TEs. We detected a similar pattern in the closely related species Zymoseptoria ardabiliae, suggesting that hybridization is widespread among these closely related grass pathogens. Overall, our results demonstrate a significant impact of recurrent hybridization on overall genome evolution of this important wheat pathogen.

Details

show
hide
Language(s): eng - English
 Dates: 2019-10-082019-10-112019-10
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1093/gbe/evz224
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Genome Biology and Evolution
  Other : GBE
  Abbreviation : Genome Biol Evol
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Oxford : Oxford Univ. Press
Pages: - Volume / Issue: 11 (11) Sequence Number: - Start / End Page: 3095 - 3105 Identifier: ISSN: 1759-6653
CoNE: https://pure.mpg.de/cone/journals/resource/1759-6653