English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  ER-phagy and human diseases

Hübner, C. A., & Đikić, I. (2019). ER-phagy and human diseases. Cell Death and Differentiation. doi:10.1038/s41418-019-0444-0.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0005-0D0E-F Version Permalink: http://hdl.handle.net/21.11116/0000-0005-0D0F-E
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Hübner, Christian A.1, Author
Đikić, Ivan2, 3, 4, Author              
Affiliations:
1Institute of Human Genetics, University Hospital Jena, Friedrich-Schiller-Universität Jena, Jena, Germany, ou_persistent22              
2Max Planck Fellow Group ER remodelling Group, Prof. Ivan Đikić, Max Planck Institute of Biophysics, Max Planck Society, ou_3004983              
3Institute of Biochemistry II, Goethe University School of Medicine, Frankfurt, Germany, ou_persistent22              
4Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Autophagy regulates the degradation of unnecessary or dysfunctional cellular components. This catabolic process requires the formation of a double-membrane vesicle, the autophagosome, that engulfs the cytosolic material and delivers it to the lysosome. Substrate specificity is achieved by autophagy receptors, which are characterized by the presence of at least one LC3-interaction region (LIR) or GABARAP-interaction motif (GIM). Only recently, several receptors that mediate the specific degradation of endoplasmic reticulum (ER) components via autophagy have been identified (the process known as ER-phagy or reticulophagy). Here, we give an update on the current knowledge about the role of ER-phagy receptors in health and disease.

Details

show
hide
Language(s):
 Dates: 2019-10-042019-09-032019-10-112019-10-28
 Publication Status: Published online
 Pages: 10
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1038/s41418-019-0444-0
BibTex Citekey: hubner_er-phagy_2019
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cell Death and Differentiation
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : E. Arnold
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: ISSN: 1350-9047
CoNE: https://pure.mpg.de/cone/journals/resource/954925616081