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  Anti-cholesterol triterpenoid acids from Saurauia vulcani Korth. (Actinidiaceae)

Musa, W. J. A., Situmeang, B., & Sianturi, J. (2019). Anti-cholesterol triterpenoid acids from Saurauia vulcani Korth. (Actinidiaceae). International journal of food properties, 22(1), 1439-1444. doi:10.1080/10942912.2019.1650762.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0005-1F1C-B Version Permalink: http://hdl.handle.net/21.11116/0000-0005-5F84-C
Genre: Journal Article

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 Creators:
Musa, Weny J. A., Author
Situmeang, Boima, Author
Sianturi, Julinton1, Author              
Affiliations:
1Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863308              

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Free keywords: anti-cholesterol; triterpenoid acids; pirdot; Saurauia vulcani Korth; Actinidiaceae
 Abstract: Two triterpenoid compounds, 3 beta-hydroxy-Olean-12-en- 28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia vulcani Korth. (Actinidiaceae). The chemical structures of compounds 1-2 were elucidated with spectroscopic data (UV, IR, H-1, C-13, DEPT 135o, HMQC, HMBC, H-1-H-1 COSY NMR) and MS as well as compared with previously reported spectra data. All the compounds were evaluated for their anti-cholesterol activity by the Liebermann-Burchard (LB) colorimetric assay. Compound 1-2 showed a remarkable anti-cholesterol activity. Most importantly, the raised concentration of 1-2 exhibited a dose-dependent manner. The discoveries of anti-cholesterol compounds 1-2 were first reported.

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Language(s): eng - English
 Dates: 2019-07-262019
 Publication Status: Published in print
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Title: International journal of food properties
Source Genre: Journal
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Publ. Info: Philadelphia : Taylor & Francis
Pages: - Volume / Issue: 22 (1) Sequence Number: - Start / End Page: 1439 - 1444 Identifier: ISSN: 1094-2912