English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Hemibiotrophic fungal pathogen induces systemic susceptibility and systemic shifts in wheat metabolome and microbiome composition

Seybold, H., Demetrowitsch, T., Hassani, M. A., Szymczak, S., Reim, E., Haueisen, J., et al. (2019). Hemibiotrophic fungal pathogen induces systemic susceptibility and systemic shifts in wheat metabolome and microbiome composition. bioRxiv. doi:10.1101/702373.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0005-1D1F-A Version Permalink: http://hdl.handle.net/21.11116/0000-0005-1D20-7
Genre: Journal Article

Files

show Files

Locators

show
hide
Locator:
Link (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Seybold, Heike1, Author              
Demetrowitsch, Tobias, Author
Hassani, M. Amine1, Author              
Szymczak, Silke, Author
Reim, Ekaterina, Author
Haueisen, Janine1, Author              
Rühlemann, Malte, Author
Franke, Andre, Author
Schwarz, Karin, Author
Stukenbrock, Eva H.1, Author              
Affiliations:
1Max Planck Fellow Group Environmental Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_2068284              

Content

show
hide
Free keywords: -
 Abstract: Yield losses caused by fungal pathogens represent a major threat to global food production. One of the most devastating fungal wheat pathogens is Zymoseptoria tritici. Despite the importance of this fungus and wheat as main staple food crop the underlying mechanisms of plant-pathogen interactions are poorly understood. Here we present a conceptual framework based on coinfection assays, comparative metabolomics, and microbiome profiling to study the interaction of Z. tritici in susceptible and resistant wheat. We demonstrate that Z. tritici suppresses the production of immune-related metabolites in a susceptible cultivar. Remarkably, this fungus-induced immune suppression spreads within the leaf and even to other leaves, a previously undescribed phenomenon that we term “}systemic induced susceptibility{”. Using a comparative metabolomics approach, we identified defense-related biosynthetic pathways that are suppressed and induced in susceptible and resistant cultivars, respectively. We show that these fungus-induced changes also dramatically affect the wheat leaf microbiome. Our findings emphasize that immune suppression by this hemibiotrophic pathogen impacts specialized plant metabolism, alters its associated microbial communities, and renders wheat vulnerable to further infections.

Details

show
hide
Language(s): eng - English
 Dates: 2019-07-142019-07-14
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1101/702373
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: bioRxiv
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: -