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  Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers

Raichlen, D. A., Pontzer, H., Harris, J. A., Mabulla, A. Z. P., Marlowe, F. W., Josh Snodgrass, J., et al. (2017). Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers. American Journal of Human Biology, 29(2): e22919. doi:10.1002/ajhb.22919.

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 Creators:
Raichlen, David A., Author
Pontzer, Herman, Author
Harris, Jacob A., Author
Mabulla, Audax Z. P., Author
Marlowe, Frank W., Author
Josh Snodgrass, J., Author
Eick, Geeta, Author
Colette Berbesque, J., Author
Sancilio, Amelia, Author
Wood, Brian M.1, Author                 
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1External Organizations, ou_persistent22              

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Free keywords: exercise, heart-rate, cholesterol, C-reactive protein, blood pressure, energetics, flex heart rate
 Abstract: Abstract Objectives Time spent in moderate-to-vigorous physical activity (MVPA) is a strong predictor of cardiovascular health, yet few humans living in industrialized societies meet current recommendations (150 min/week). Researchers have long suggested that human physiological requirements for aerobic exercise reflect an evolutionary shift to a hunting and gathering foraging strategy, and a recent transition to more sedentary lifestyles likely represents a mismatch with our past in terms of physical activity. The goal of this study is to explore this mismatch by characterizing MVPA and cardiovascular health in the Hadza, a modern hunting and gathering population living in Northern Tanzania. Methods We measured MVPA using continuous heart rate monitoring in 46 participants recruited from two Hadza camps. As part of a larger survey of health in the Hadza, we measured blood pressure (n = 198) and biomarkers of cardiovascular health (n = 23) including C-reactive protein, cholesterol (Total, HDL, and LDL), and triglycerides. Results We show that Hadza participants spend large amounts of time in MVPA (134.92 ± 8.6 min/day), and maintain these activity levels across the lifespan. In fact, the Hadza engage in over 14 times as much MVPA as subjects participating in large epidemiological studies in the United States. We found no evidence of risk factors for cardiovascular disease in this population (low prevalence of hypertension across the lifespan, optimal levels for biomarkers of cardiovascular health). Conclusions Our results provide evidence that the hunting and gathering foraging strategy involves high levels of MVPA, supporting the evolutionary medicine model for the relationship between MVPA and cardiovascular health.

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Language(s): eng - English
 Dates: 2017
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: DOI: 10.1002/ajhb.22919
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Title: American Journal of Human Biology
Source Genre: Journal
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Pages: - Volume / Issue: 29 (2) Sequence Number: e22919 Start / End Page: - Identifier: -