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  Angiotensin II, But Not Norepinephrine and Sodium Nitroprusside, Decreases the Renal BOLD Signal

Klarhöfer, M., Schächinger, H., Drewe, J., & Scheffler, K. (2005). Angiotensin II, But Not Norepinephrine and Sodium Nitroprusside, Decreases the Renal BOLD Signal. In 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005).

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Klarhöfer, M, Author
Schächinger, H, Author
Drewe, J, Author
Scheffler, K1, Author              
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1External Organizations, ou_persistent22              

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 Abstract: Purpose of the study was to evaluate the potential of BOLD fMRI techniques to assess angiotensin II (A2) induced renovascular responsiveness. The effect of A2 on kidney T2* was compared to the effect of other vasoactive susbstances like sodium nitroprusside (SNP) or norepinephrine (NE). To avoid motion artifacts and to obtain a good temporal resolution a multi-echo EPI technique was used. A2 caused a shortening of T2* between 6\% and 10\%, whereas neither SNP nor NE lead to significant changes in T2*. It can be concluded that BOLD MRI is suitable to assess A2-induced responsiveness of the renal vasculature.

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 Dates: 2005-05
 Publication Status: Published online
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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Place of Event: Miami Beach, FL, USA
Start-/End Date: 2005-05-07 - 2005-05-13

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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 558 Start / End Page: - Identifier: -