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  Tonotopic mapping of the mouse auditory midbrain with Mn-enhanced MRI,

Yu, X., Wadghiri, Y., Sanes, D., & Turnbull, D. (2005). Tonotopic mapping of the mouse auditory midbrain with Mn-enhanced MRI,. In 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005).

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Yu, X1, Author              
Wadghiri, YZ, Author
Sanes, DH, Author
Turnbull, DH, Author
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1External Organizations, ou_persistent22              

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 Abstract: To examine the spatial sensitivity of Mn-enhanced MRI (MEMRI) for neuronal activity mapping, we detected sound-evoked activity patterns in the auditory midbrain of mice. After mice were exposed to different sound stimuli, and the signal enhancement patterns were compared with tonotopic (iso-frequency) maps derived from electrophysiological recordings. Consistent with the published tonotopic maps of the mouse inferior colliculus (IC), MEMRI revealed that low-to-high frequency components in sound stimuli are encoded in dorsal-to-ventral neuronal populations of the IC. Significantly, MEMRI also provides more elaborate neuronal activity representations corresponding to defined frequency and amplitude components to the acoustic stimulus.

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 Dates: 2005-05
 Publication Status: Published online
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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Place of Event: Miami Beach, FL, USA
Start-/End Date: 2005-05-07 - 2005-05-13

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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 401 Start / End Page: - Identifier: -