English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Spiral wave unpinning facilitated by wave emitting sites in cardiac monolayers

Punacha, S., Berg, S., Sebastian, A., Krinsky, V. I., Luther, S., & Shajaha, T. K. (2019). Spiral wave unpinning facilitated by wave emitting sites in cardiac monolayers. Proceedings - Royal Society. Mathematical, physical and engineering sciences, 475(2230): 20190420. doi:10.1098/rspa.2019.0420.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0005-486C-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-486D-1
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Punacha, S., Author
Berg, Sebastian1, Author              
Sebastian, A., Author
Krinsky, Valentin I.1, Author              
Luther, Stefan1, Author              
Shajaha, T. K., Author
Affiliations:
1Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063288              

Content

show
hide
Free keywords: cardiac arrhythmia; excitable media; spiral waves; unpinning window
 Abstract: Rotating spiral waves of electrical activity in the heart can anchor to unexcitable tissue (an obstacle) and become stable pinned waves. A pinned rotating wave can be unpinned either by a local electrical stimulus applied close to the spiral core, or by an electric field pulse that excites the core of a pinned wave independently of its localization. The wave will be unpinned only when the pulse is delivered inside a narrow time interval called the unpinning window (UW) of the spiral. In experiments with cardiac monolayers, we found that other obstacles situated near the pinning centre of the spiral can facilitate unpinning. In numerical simulations, we found increasing or decreasing of the UW depending on the location, orientation and distance between the pinning centre and an obstacle. Our study indicates that multiple obstacles could contribute to unpinning in experiments with intact hearts.

Details

show
hide
Language(s): eng - English
 Dates: 2019-10-16
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1098/rspa.2019.0420
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Proceedings - Royal Society. Mathematical, physical and engineering sciences
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: 11 Volume / Issue: 475 (2230) Sequence Number: 20190420 Start / End Page: - Identifier: -