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  Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)-From trajectories to mechanisms and interventions

Heinz, A., Kiefer, F., Smolka, M., Endrass, T., Beste, C., Beck, A., et al. (2020). Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)-From trajectories to mechanisms and interventions. Addiction Biology, 25(2), 1-6. doi:10.1111/adb.12866.

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 Urheber:
Heinz, A, Autor
Kiefer, F, Autor
Smolka, MN, Autor
Endrass, T, Autor
Beste, C, Autor
Beck, A, Autor
Liu, S, Autor
Genauck , A, Autor
Romund, L, Autor
Banaschewski, T, Autor
Bermpohl, F, Autor
Derserno, L, Autor
Dolan, RJ, Autor
Durstewitz, D, Autor
Ebner-Priemer, U, Autor
Flor, H, Autor
Hansson, AC, Autor
Heim, C, Autor
Hermann, D, Autor
Kiebel, S, Autor
Kirsch, P, AutorKirschbaum, C, AutorKoppe, G, AutorMarxen, M, AutorMeyer-Lindenberg , A, AutorNagel, WE, AutorNoori, HR1, 2, Autor           Pilhatsch, M, AutorPriller, J, AutorRietschel, M, AutorRomanczuk-Seiferth, N, AutorSchlagenhauf, F, AutorSommer, WH, AutorStallkamp, J, AutorStröhle, A, AutorStock, AC, AutorWinterer, G, AutorWinter, C, AutorWalter, H, AutorWitt, S, AutorVollstädt-Klein, S, AutorRapp, MA, AutorTost, H, AutorSpanagel, R, Autor mehr..
Affiliations:
1Research Group Neuronal Convergence, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528694              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Zusammenfassung: One of the major risk factors for global death and disability is alcohol, tobacco, and illicit drug use. While there is increasing knowledge with respect to individual factors promoting the initiation and maintenance of substance use disorders (SUDs), disease trajectories involved in losing and regaining control over drug intake (ReCoDe) are still not well described. Our newly formed German Collaborative Research Centre (CRC) on ReCoDe has an interdisciplinary approach funded by the German Research Foundation (DFG) with a 12-year perspective. The main goals of our research consortium are (i) to identify triggers and modifying factors that longitudinally modulate the trajectories of losing and regaining control over drug consumption in real life, (ii) to study underlying behavioral, cognitive, and neurobiological mechanisms, and (iii) to implicate mechanism-based interventions. These goals will be achieved by: (i) using mobile health (m-health) tools to longitudinally monitor the effects of triggers (drug cues, stressors, and priming doses) and modify factors (eg, age, gender, physical activity, and cognitive control) on drug consumption patterns in real-life conditions and in animal models of addiction; (ii) the identification and computational modeling of key mechanisms mediating the effects of such triggers and modifying factors on goal-directed, habitual, and compulsive aspects of behavior from human studies and animal models; and (iii) developing and testing interventions that specifically target the underlying mechanisms for regaining control over drug intake.

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 Datum: 2019-122020-03
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1111/adb.12866
eDoc: e12866
 Art des Abschluß: -

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Titel: Addiction Biology
  Andere : Addict. Biol.
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: Abingdon, Oxfordshire, UK : Carfax
Seiten: - Band / Heft: 25 (2) Artikelnummer: - Start- / Endseite: 1 - 6 Identifikator: ISSN: 1355-6215
CoNE: https://pure.mpg.de/cone/journals/resource/954925277561