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  The influence of steroidal and triterpenoid saponins on monolayer models of the outer leaflets of human erythrocytes, E. coli and S. cerevisiae cell membranes

Orczyk, M., Wojciechowski, K., & Brezesinski, G. (2020). The influence of steroidal and triterpenoid saponins on monolayer models of the outer leaflets of human erythrocytes, E. coli and S. cerevisiae cell membranes. Journal of Colloid and Interface Science, 563, 207-217. doi:10.1016/j.jcis.2019.12.014.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0005-6FA8-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-6FA9-1
Genre: Journal Article

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Orczyk, M., Author
Wojciechowski, K., Author
Brezesinski, Gerald1, Author              
Affiliations:
1Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863284              

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Free keywords: Digitonin, bark saponin, Phospholipids, Sterols, Fluorescence microscopy, Langmuir monolayer, IRRAS
 Abstract: The present paper discusses the use of monolayers of lipid mixtures mimicking the composition of biological membranes of bacteria, erythrocyte and yeast in the context of the anti-bacterial, hemolytic and anti-fungal activity of saponins. Saponins are plant-produced glycosidic biosurfactants with either steroidal or triterpenoidal aglycone. In the present study we used digitonin as a representative steroidal saponin (extracted from Digitalis purpurea) and a mixture of triterpenoid saponins from Quillaja saponaria Molina. The effect of saponins was studied first on monolayers consisting of single lipids characteristic for the given type of biological membrane, and then

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Language(s): eng - English
 Dates: 2019-12-142020
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: -
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Title: Journal of Colloid and Interface Science
  Abbreviation : J. Colloid Interface Sci.
Source Genre: Journal
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Publ. Info: Amsterdam etc. : Elsevier Inc.
Pages: - Volume / Issue: 563 Sequence Number: - Start / End Page: 207 - 217 Identifier: ISSN: 0021-9797