Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First 
Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine 
Dimethylaminohydrolase-1 (hDDAH-1)

Lunk, Ina; Litty, Felix-Alexander; Hennig, Sven; Vetter, Ingrid R.; Kotthaus, Jürke; Altmann, Karin S.; Ott, Gudrun; Havemeyer, Antje; García , Carmen Carrillo; Clement, Bernd; Schade, Dennis

doi:10.1021/acs.jmedchem.9b01230

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Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1)

Lunk, I., Litty, F.-A., Hennig, S., Vetter, I. R., Kotthaus, J., Altmann, K. S., et al. (2019). Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). Journal of Medicinal Chemistry, 63(1), 425-432. doi:10.1021/acs.jmedchem.9b01230.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0005-69DE-C Version Permalink: https://hdl.handle.net/21.11116/0000-0005-9268-1

Genre: Journal Article

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Creators:
Lunk, Ina¹, Author
Litty, Felix-Alexander¹, Author
Hennig, Sven¹, Author
Vetter, Ingrid R.², Author
Kotthaus, Jürke¹, Author
Altmann, Karin S.¹, Author
Ott, Gudrun¹, Author
Havemeyer, Antje¹, Author
García , Carmen Carrillo¹, Author
Clement, Bernd¹, Author
Schade, Dennis¹, Author

Affiliations:
1External Organizations, ou_persistent22
2Abt. I:Mechanistische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753287

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Language(s): eng - English

Dates: Date issued: 2019-12

Publication Status: Issued

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Rev. Type: Peer

Identifiers: DOI: 10.1021/acs.jmedchem.9b01230

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Title: Journal of Medicinal Chemistry

Source Genre: Journal

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Publ. Info: Washington DC : ACS Publications

Pages: - Volume / Issue: 63 (1) Sequence Number: - Start / End Page: 425 - 432 Identifier: ISSN: 0022-2623
CoNE: https://pure.mpg.de/cone/journals/resource/110992357271168