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Abstract:
Short-lasting patterns of neural activity, including single- or multiple-cycle oscillatory episodes, such as spindles, ripples & PGO waves, likely reflect state changes of self-organizing large-scale networks. Although such neural events were studied in detail with neurophysiological methods, the brain-states related to them remain elusive, primarily due to a dearth of methodologies permitting concurrent recordings in various structures and mapping of whole-brain activity. In my lectures, I will thoroughly describe our multidisciplinary and multimodal approaches, and subsequently present novel results related to the interaction of ripples and PGO waves, questioning the global nature of sleep-states.