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  Invariance of stoichiometry of the sarcoplasmic reticulum calcium pump at physiological calcium concentrations--a reevaluation

Hasselbach, W., & Migala, A. (1985). Invariance of stoichiometry of the sarcoplasmic reticulum calcium pump at physiological calcium concentrations--a reevaluation. Zeitschrift für Naturforschung, C: Journal of Biosciences, 40(7-8), 571-575. doi:10.1515/znc-1985-7-821.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0005-9609-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0005-960A-7
Genre: Journal Article
Alternative Title : Invariance of Stoichiometry of the Sarcoplasmic Reticulum Calcium Pump at Physiological Calcium Concentrations – a Reevaluation

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 Creators:
Hasselbach, Wilhelm1, Author           
Migala, Andrea2, Author           
Affiliations:
1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              
2Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              

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Free keywords: Sarcoplasmic Reticulum; Calcium Pump; Stoichiometry
 Abstract: The decline of the transport ratio of the sarcoplasmic calcium pump observed in a recent study (A. results from the retardation of calcium oxalate precipitation at low calcium/protein ratios. The prevailing high internal calcium level supports a rapid calcium backflux and a compensatory ATP hydrolysis during net calcium uptake which reduces the transport ratio. Yet, the determined calcium back­ flux does not fully account for the decline of the transport ratio. A supposed modulation of the stoichiometry of the pump by external calcium (0.1 μм) is at variance with results of previous studies showing a constant transport ratio of two in the same calcium concentration range.

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Language(s): eng - English
 Dates: 1985-05-202014-06-021985-07-01
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1515/znc-1985-7-821
URI: https://www.ncbi.nlm.nih.gov/pubmed/2413640
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Title: Zeitschrift für Naturforschung, C: Journal of Biosciences
  Abbreviation : Z. Naturforsch., C: J. Biosci.
Source Genre: Journal
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Publ. Info: Berlin : Walter de Gruyter GmbH
Pages: - Volume / Issue: 40 (7-8) Sequence Number: - Start / End Page: 571 - 575 Identifier: ISSN: 1865-7125
CoNE: https://pure.mpg.de/cone/journals/resource/954927655916_1