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  Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

Lepeltier, E., Nuhn, L., Lehr, C.-M., & Zentel, R. (2015). Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine. Nanomedicine, 10(20), 3147-3166. doi:10.2217/nnm.15.132.

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 Creators:
Lepeltier, Elise, Author
Nuhn, Lutz1, Author           
Lehr, Claus-Michael, Author
Zentel, Rudolf, Author
Affiliations:
1Univ Ghent, Dept Pharmaceut, Ghent, Belgium, ou_persistent22              

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 Abstract: During the last 3 decades, nanomedicines have provided novel opportunities to improve the delivery of chemotherapeutics in cancer therapy effectively. However, many principles learnt from there have the potential to be transferred to other diseases. This perspective article, on the one hand, critically reflects the limitations of nanomedicines in tumor therapy and, on the other hand, provides alternative examples of nanomedicinal applications in immunotherapy, noninvasive drug deliveries across epithelial barriers and strategies to combat intra- and extra-cellular bacterial infections. Looking ahead, access to highly complex nanoparticular delivery vehicles given nowadays may allow further improved therapeutic concepts against several diseases in the future too.

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Language(s): eng - English
 Dates: 2015
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.2217/nnm.15.132
 Degree: -

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Title: Nanomedicine
Source Genre: Journal
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Publ. Info: London, UK : Future Medicine Ltd
Pages: - Volume / Issue: 10 (20) Sequence Number: - Start / End Page: 3147 - 3166 Identifier: ISSN: 1743-5889
CoNE: https://pure.mpg.de/cone/journals/resource/1743-5889