ausblenden:
Schlagwörter:
antitumor vaccines, HPMA, MUC1 glycopeptides, polymer glycopeptide conjugates, T-helper-cell epitope peptides
Zusammenfassung:
Highly decorated: Tumor-associated MUC1 glycopeptide and tetanus toxoid T-cell epitope P2 can be attached to water-soluble poly(N-(2-hydroxypropyl)methacrylamide) carriers by orthogonal ligation techniques. Fully synthetic vaccine A with additional nanostructure-promoting domains induced antibodies that exhibit high affinity to tumor cells.