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  Why does early childhood deprivation increase the risk for depression and anxiety in adulthood? A developmental cascade model

Golm, D., Maughan, B., Barker, E. D., Hill, J., Kennedy, M., Knights, N., et al. (2020). Why does early childhood deprivation increase the risk for depression and anxiety in adulthood? A developmental cascade model. The Journal of Child Psychology and Psychiatry. doi:10.1111/jcpp.13205.

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sci-18-sch-01-why.pdf (Verlagsversion), 246KB
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© 2020 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

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 Urheber:
Golm, Dennis1, Autor
Maughan, Barbara2, Autor
Barker, Edward D.3, Autor
Hill, Jonathan4, Autor
Kennedy, Mark5, Autor
Knights, Nicky6, Autor
Kreppner, Jana7, Autor
Kumsta, Robert8, Autor
Schlotz, Wolff9, Autor           
Rutter, Michael2, Autor
Sonuga‐Barke, Edmund J.S.5, Autor
Affiliations:
1Centre for Innovation in Mental Health, School of Psychology, University of Southampton, Southampton, UK, ou_persistent22              
2Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK, ou_persistent22              
3Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London , London, UK, ou_persistent22              
4School of Psychology & Clinical Language Sciences, University of Reading, Reading, UK, ou_persistent22              
5Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK, ou_persistent22              
6Department of Psychology, Centre for Clinical and Community Applications of Health Psychology, University of Southampton, Southampton, UK, ou_persistent22              
7Centre for Innovation in Mental Health, School of Psychology, University of Southampton , Southampton, UK, ou_persistent22              
8Department of Genetic Psychology, Faculty of Psychology, Ruhr University Bochum, Bochum, Germany, ou_persistent22              
9Scientific Services, Max Planck Institute for Empirical Aesthetics, Max Planck Society, ou_2421698              

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Schlagwörter: Institutional deprivation, depression, anxiety, emotional problems, developmental cascades, neurodevelopmental problems, longitudinal, prospective, natural experiment
 Zusammenfassung: Background: Using data from the English & Romanian Adoptees (ERA) study, we recently reported that early timelimited
exposure to severe institutional deprivation is associated with early-onset and persistent neurodevelopmental
problems and later-onset emotional problems. Here, we examine possible reasons for the late emergence of emotional
problems in this cohort. Our main focus is on testing a developmental cascade mediated via the functional impact of
early-appearing neurodevelopmental problems on late adolescent functioning. We also explore a second putative
pathway via sensitization to stress. Methods: The ERA study includes 165 Romanian individuals who spent their
early lives in grossly depriving institutions and were subsequently adopted into UK families, along with 52 UK
adoptees with no history of deprivation. Age six years symptoms of neurodevelopmental problems and age 15
anxiety/depression symptoms were assessed via parental reports. Young adult symptoms of depression and anxiety
were assessed by both parent and self-reports; young adults also completed measures of stress reactivity, exposure
to adverse life events, and functioning in work and interpersonal relationships. Results: The path between early
institutional deprivation and adult emotional problems was mediated via the impact of early neurodevelopmental
problems on unemployment and poor friendship functioning during the transition to adulthood. The findings with
regard to early deprivation, later life stress reactivity, and emotional problems were inconclusive. Conclusions: Our
analysis suggests that the risk for adult depression and anxiety following extreme institutional deprivation is
explained through the effects of early neurodevelopmental problems on later social and vocational functioning.
Future research should more fully examine the role of stress susceptibility in this model. Keywords: Institutional
deprivation; depression; anxiety; emotional problems; developmental cascades; neurodevelopmental problems;
longitudinal; prospective; natural experiment.

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 Datum: 2020-02-06
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1111/jcpp.13205
 Art des Abschluß: -

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Titel: The Journal of Child Psychology and Psychiatry
Genre der Quelle: Zeitschrift
 Urheber:
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Ort, Verlag, Ausgabe: Oxford : Wiley-Blackwell
Seiten: - Band / Heft: - Artikelnummer: - Start- / Endseite: - Identifikator: ISSN: 1469-7610