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  Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia

Marcus, J. H., Posth, C., Ringbauer, H., Lai, L., Skeates, R., Sidore, C., et al. (2020). Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia. Nature Communications, 11(1): 939, pp. 1-14. doi:10.1038/s41467-020-14523-6.

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Other : Population history from the Neolithic to present on the Mediterranean island of Sardinia: an ancient DNA perspective [title of preprint]

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 Creators:
Marcus, Joseph H., Author
Posth, Cosimo1, Author           
Ringbauer, Harald, Author
Lai, Luca, Author
Skeates, Robin, Author
Sidore, Carlo, Author
Beckett, Jessica, Author
Furtwängler, Anja, Author
Olivieri, Anna, Author
Chiang, Charleston W. K., Author
Al-Asadi, Hussein, Author
Dey, Kushal, Author
Joseph, Tyler A., Author
Liu, Chi-Chun, Author
Der Sarkissian, Clio, Author
Radzeviciute, Rita1, Author           
Michel, Megan2, Author           
Gradoli, Maria Giuseppina, Author
Marongiu, Patrizia, Author
Rubino, Salvatore, Author
Mazzarello, Vittorio, AuthorRovina, Daniela, AuthorLa Fragola, Alessandra, AuthorSerra, Rita Maria, AuthorBandiera, Pasquale, AuthorBianucci, Raffaella, AuthorPompianu, Elisa, AuthorMurgia, Clizia, AuthorGuirguis, Michele, AuthorOrquin, Rosana Pla, AuthorTuross, Noreen, Authorvan Dommelen, Peter, AuthorHaak, Wolfgang1, Author           Reich, David, AuthorSchlessinger, David, AuthorCucca, Francesco, AuthorKrause, Johannes2, Author           Novembre, John, Author more..
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              
2MHAAM, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2541699              

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 Abstract: The island of Sardinia has been of particular interest to geneticists for decades. The current model for Sardinia’s genetic history describes the island as harboring a founder population that was established largely from the Neolithic peoples of southern Europe and remained isolated from later Bronze Age expansions on the mainland. To evaluate this model, we generate genome-wide ancient DNA data for 70 individuals from 21 Sardinian archaeological sites spanning the Middle Neolithic through the Medieval period. The earliest individuals show a strong affinity to western Mediterranean Neolithic populations, followed by an extended period of genetic continuity on the island through the Nuragic period (second millennium BCE). Beginning with individuals from Phoenician/Punic sites (first millennium BCE), we observe spatially-varying signals of admixture with sources principally from the eastern and northern Mediterranean. Overall, our analysis sheds light on the genetic history of Sardinia, revealing how relationships to mainland populations shifted over time.

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Language(s): eng - English
 Dates: 2019-03-212020-01-082020-02-242020
 Publication Status: Issued
 Pages: 14
 Publishing info: -
 Table of Contents: Results
Ancient DNA from Sardinia.
Similarity to western mainland Neolithic populations.
Continuity from the Middle Neolithic through the Nuragic.
From the Nuragic period to present-day Sardinia: signatures of admixture.
Refined signatures of post-Nuragic admixture and heterogeneity.
Fine-scale structure in contemporary Sardinia.
Discussion
Methods
Archeological sampling.
Initial sample screening and sequencing.
Processing of mtDNA data.
Inference of Y haplogroups.
Merging newly generated data with published data.
Principal components analysis.
ADMIXTURE analysis.
Estimation of f-statistics.
Estimation of FST-coefficients.
Estimation of admixture proportions and model testing with qpAdm.
 Rev. Type: Peer
 Identifiers: DOI: 10.1038/s41467-020-14523-6
Other: shh2525
 Degree: -

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Title: Nature Communications
  Abbreviation : Nat. Commun.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 11 (1) Sequence Number: 939 Start / End Page: 1 - 14 Identifier: ISSN: 2041-1723
CoNE: https://pure.mpg.de/cone/journals/resource/2041-1723