English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

Rambold, A., & Pearce, E. L. (2018). Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function. Trends in Immunology, 39, 6-18. doi:10.1016/j.it.2017.08.006.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0005-C40C-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-C40D-0
Genre: Journal Article

Files

show Files
hide Files
:
Rambold et al..pdf (Publisher version), 3MB
Name:
Rambold et al..pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
cc-by-nc/4.0

Creators

show
hide
 Creators:
Rambold, Angelika1, Author              
Pearce, Erika L.1, Author              
Affiliations:
1Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243650              

Content

show
hide
Free keywords: -
 Abstract: Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the synthesis of macromolecules and post-translational modifications. The many processes that occur in mitochondria are intimately linked to their morphology that is shaped by opposing fusion and fission events. Exciting evidence is now emerging that demonstrates reciprocal crosstalk between mitochondrial dynamics and metabolism. Metabolic cues can control the mitochondrial fission and fusion machinery to acquire specific morphologies that shape their activity. We review the dynamic properties of mitochondria and discuss how these organelles interlace with immune cell metabolism and function.

Details

show
hide
Language(s): eng - English
 Dates: 2018-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.it.2017.08.006
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Trends in Immunology
  Other : Trends Immunol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Oxford, UK : Elsevier Current Trends
Pages: - Volume / Issue: 39 Sequence Number: - Start / End Page: 6 - 18 Identifier: ISSN: 1471-4906
CoNE: https://pure.mpg.de/cone/journals/resource/954925482652_1