English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mechanochemical enzymes and protein machines as hydrodynamic force dipoles: The active dimer model

Hosaka, Y., Komura, S., & Mikhailov, A. S. (2020). Mechanochemical enzymes and protein machines as hydrodynamic force dipoles: The active dimer model. Soft Matter, 16(47), 10734-10749. doi:10.1039/D0SM01138J.

Item is

Files

show Files
hide Files
:
2003.02574.pdf (Preprint), 579KB
Name:
2003.02574.pdf
Description:
File downloaded from arXiv at 2020-03-11 14:59
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
:
d0sm01138j.pdf (Publisher version), 3MB
Name:
d0sm01138j.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
2020
Copyright Info:
The Author(s)

Locators

show

Creators

show
hide
 Creators:
Hosaka, Yuto1, Author
Komura, Shigeyuki1, Author
Mikhailov, Alexander S.2, 3, Author           
Affiliations:
1Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo 192-0397, Japan, ou_persistent22              
2Physical Chemistry, Fritz Haber Institute, Max Planck Society, ou_634546              
3Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan, ou_persistent22              

Content

show
hide
Free keywords: Condensed Matter, Soft Condensed Matter, cond-mat.soft
 Abstract: Mechanochemically active enzymes change their shapes within every turnover
cycle. Therefore, they induce circulating flows in the solvent around them and
behave as oscillating hydrodynamic force dipoles. Because of non-equilibrium
fluctuating flows collectively generated by the enzymes, mixing in the solution
and diffusion of passive particles within it are expected to get enhanced.
Here, we investigate the intensity and statistical properties of such force
dipoles in the minimal active dimer model of a mechanochemical enzyme. In the
framework of this model, novel estimates for hydrodynamic collective effects in
solution and in lipid bilayers under rapid rotational diffusion are derived,
and available experimental and computational data is examined.

Details

show
hide
Language(s): eng - English
 Dates: 2020-03-052020-06-222020-09-142020-12-21
 Publication Status: Published online
 Pages: 16
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Soft Matter
  Abbreviation : Soft Matter
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Royal Society of Chemistry
Pages: 16 Volume / Issue: 16 (47) Sequence Number: - Start / End Page: 10734 - 10749 Identifier: ISSN: 1744-683X
CoNE: https://pure.mpg.de/cone/journals/resource/1744-683X