ausblenden:
Schlagwörter:
Brønsted acids; cyclohexadienones; Diels–Alder reaction; imidodiphosphorimidates; organocatalysis
Zusammenfassung:
We describe a highly enantioselective Diels–Alder reaction of cross‐conjugated cyclohexadienones with cyclopentadiene, in which five stereocenters are effectively controlled by a strongly acidic and confined imidodiphosphorimidate catalyst. Our approach provides tricyclic products in excellent stereoselectivity. We also report methods to convert the obtained products into useful intermediates and a computational study that aids in gaining deeper insight into the reaction mechanism and origin of stereoselectivity