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  Modified Hebbian Rule for Synaptic Enhancement in the Hippocampus and the Visual Cortex

Bonhoeffer, T., Kossel, A., Bolz, J., & Aertsen, A. (1990). Modified Hebbian Rule for Synaptic Enhancement in the Hippocampus and the Visual Cortex. Cold Spring Harbor Symposia on Quantitative Biology, 55, 137-146. doi:10.1101/SQB.1990.055.01.017.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-0C42-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-3A45-C
Genre: Journal Article

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http://symposium.cshlp.org/content/55/137 (Publisher version)
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 Creators:
Bonhoeffer, T1, 2, Author              
Kossel, A3, Author              
Bolz, J3, Author
Aertsen, A1, 2, Author              
Affiliations:
1Former Department Structure and Function of Natural Nerve-Net , Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497803              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
3Friedrich Miescher Laboratory, Max Planck Society, Max-Planck-Ring 9, 72076 Tübingen, DE, ou_2575692              

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 Abstract: Ramón y Cajal (1909, 1911) was the first to suggest that synapses might be the locations at which memory is laid down in the brain. Some 50 years later, Donald Hebb proposed the physiological condition under which this might happen (Hebb 1949). He invoked the notion of “synaptic plasticity”: Activity occurring simultaneously at the neurons pre- and postsynaptic to a particular synapse would lead to an increase in the efficacy of that synapse. This postulate later became known as the Hebb rule and was widely adopted by both experimentors and theoreticians. Hebb's model of synaptic plasticity provided a natural explanation for many experimental observations on learning, memory, and development.

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 Dates: 1990
 Publication Status: Published in print
 Pages: -
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 Rev. Method: -
 Identifiers: DOI: 10.1101/SQB.1990.055.01.017
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Title: Cold Spring Harbor Symposia on Quantitative Biology
Source Genre: Journal
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Publ. Info: Cold Spring Harbor, L.I., N.Y. : Biological Laboratory
Pages: - Volume / Issue: 55 Sequence Number: - Start / End Page: 137 - 146 Identifier: ISSN: 0091-7451
CoNE: https://pure.mpg.de/cone/journals/resource/954925463169