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  Conformational studies of oligosaccharides

Yu, Y., & Delbianco, M. (2020). Conformational studies of oligosaccharides. Chemistry – A European Journal, 26(44), 9814-9825. doi:10.1002/chem.202001370.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-453F-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-DB31-C
Genre: Journal Article

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 Creators:
Yu, Yang1, Author              
Delbianco, Martina1, Author              
Affiliations:
1Martina Delbianco, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2559692              

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Free keywords: glycans, structural studies, conformations, synthetic oligosaccharides
 Abstract: The conformation of a molecule strongly affects its function, as demonstrated for peptides and nucleic acids. This correlation is much less established for carbohydrates, the most abundant organic materials in Nature. Recent advances in synthetic and analytical techniques have enabled the study of carbohydrates at the molecular level. Recurrent structural features were identified as responsible for particular biological activities or material properties. Here, we discuss the recent achievements in the structural characterization of carbohydrates, enabled by systematic studies of chemically defined oligosaccharides. These findings can guide the development of more potent glycomimetics. Synthetic carbohydrate materials by design can be envisioned.

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Language(s): eng - English
 Dates: 2020-04-242020
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/chem.202001370
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Title: Chemistry – A European Journal
  Other : Chem. – Eur. J.
  Other : Chem. Eur. J.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 26 (44) Sequence Number: - Start / End Page: 9814 - 9825 Identifier: ISSN: 0947-6539