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  Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations

Maudsley, A., Andronesi, O., Barker, P., Bizzi, A., Bogner, W., Henning, A., et al. (2020). Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations. NMR in Biomedicine, Epub ahead. doi:10.1002/nbm.4309.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-5025-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-5026-5
Genre: Journal Article

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Maudsley, AA, Author
Andronesi, OC, Author
Barker, PB, Author
Bizzi, A, Author
Bogner, W, Author
Henning, A1, 2, Author              
Nelson, SJ, Author
Posse, S, Author
Shungu, DC, Author
Soher, BJ, Author
Affiliations:
1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Magnetic resonance spectroscopic imaging (MRSI) offers considerable promise for monitoring metabolic alterations associated with disease or injury; however, to date, these methods have not had a significant impact on clinical care, and their use remains largely confined to the research community and a limited number of clinical sites. The MRSI methods currently implemented on clinical MRI instruments have remained essentially unchanged for two decades, with only incremental improvements in sequence implementation. During this time, a number of technological developments have taken place that have already greatly benefited the quality of MRSI measurements within the research community and which promise to bring advanced MRSI studies to the point where the technique becomes a true imaging modality, while making the traditional review of individual spectra a secondary requirement. Furthermore, the increasing use of biomedical MR spectroscopy studies has indicated clinical areas where advanced MRSI methods can provide valuable information for clinical care. In light of this rapidly changing technological environment and growing understanding of the value of MRSI studies for biomedical studies, this article presents a consensus from a group of experts in the field that reviews the state-of-the-art for clinical proton MRSI studies of the human brain, recommends minimal standards for further development of vendor-provided MRSI implementations, and identifies areas which need further technical development.

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 Dates: 2020-04
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/nbm.4309
eDoc: e4309
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Title: NMR in Biomedicine
Source Genre: Journal
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Publ. Info: London : Heyden & Son
Pages: - Volume / Issue: Epub ahead Sequence Number: - Start / End Page: - Identifier: ISSN: 0952-3480
CoNE: https://pure.mpg.de/cone/journals/resource/954925574973