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  Extracellular Marking and Retrograde Labelling of Neurons

Wässle, H., & Hausen, K. (1981). Extracellular Marking and Retrograde Labelling of Neurons. In C. Heym, & W.-G. Forssmann (Eds.), Techniques in Neuroanatomical Research (pp. 317-338). Berlin, Germany: Springer.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-50C2-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-50F0-0
Genre: Book Chapter

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 Creators:
Wässle, H1, Author              
Hausen, K2, 3, Author              
Affiliations:
1Friedrich Miescher Laboratory, Max Planck Society, Max-Planck-Ring 9, 72076 Tübingen, DE, ou_2575692              
2Former Department Information Processing in Insects, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497801              
3Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Microelectrodes of different types are used by neurophysiologists to record the electrical activity of single nerve cells or groups of neurons, and it is often desirable to localize the structure producing the physiological response. Ideally the nerve cells whose activity is being monitored should be anatomically characterized. With intracellular recording of a single neuron, a stain can be iontophoretically injected into the neuroplasm, and the cell unambiguously identified. Such recordings, however, are very difficult to achieve in the mammalian brain, and most experimenters still rely on extracellular recordings for their physiological analysis. Although it is not generally possible to identify the recorded structure to the neuronal level using extracellular techniques, the ordered topology of some structures in the brain, such as cerebellum, hippocampus, and retina, may permit cellular identification if the tip position of the microelectrode can be accurately marked.

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 Dates: 1981
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1007/978-3-642-68029-8_19
 Degree: -

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Title: Techniques in Neuroanatomical Research
Source Genre: Book
 Creator(s):
Heym, C, Editor
Forssmann, W-G, Editor
Affiliations:
-
Publ. Info: Berlin, Germany : Springer
Pages: 395 Volume / Issue: - Sequence Number: - Start / End Page: 317 - 338 Identifier: ISBN: 3-540-10686-3