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  Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis.

Marbach-Breitrück, E., Matz-Soja, M., Abraham, U., Schmidt-Heck, W., Sales, S., Rennert, C., et al. (2019). Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis. Journal of hepatology, 70(6), 1192-1202. doi:10.1016/j.jhep.2019.01.022.

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 Creators:
Marbach-Breitrück, Eugenia, Author
Matz-Soja, Madlen, Author
Abraham, Ute, Author
Schmidt-Heck, Wolfgang, Author
Sales, Susanne1, Author           
Rennert, Christiane, Author
Kern, Matthias, Author
Aleithe, Susanne, Author
Spormann, Luise, Author
Thiel, Carlo, Author
Gerlini, Raffaele, Author
Arnold, Katrin, Author
Klöting, Nora, Author
Guthke, Reinhard, Author
Rozman, Damjana, Author
Teperino, Raffaele, Author
Shevchenko, Andrej1, Author           
Kramer, Achim, Author
Gebhardt, Rolf, Author
Affiliations:
1Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692              

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 Abstract: The mammalian circadian clock controls various aspects of liver metabolism and integrates nutritional signals. Recently, we described Hedgehog (Hh) signaling as a novel regulator of liver lipid metabolism. Herein, we investigated crosstalk between hepatic Hh signaling and circadian rhythm.

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 Dates: 2019-06-01
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.jhep.2019.01.022
Other: cbg-7353
PMID: 30711403
 Degree: -

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Title: Journal of hepatology
  Other : J Hepatol
Source Genre: Journal
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Pages: - Volume / Issue: 70 (6) Sequence Number: - Start / End Page: 1192 - 1202 Identifier: -