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  Ancient genome-wide DNA from France highlights the complexity of interactions between Mesolithic hunter-gatherers and Neolithic farmers

Rivollat, M., Jeong, C., Schiffels, S., Kücükkalıpcı, İ., Pemonge, M.-H., Rohrlach, A. B., et al. (2020). Ancient genome-wide DNA from France highlights the complexity of interactions between Mesolithic hunter-gatherers and Neolithic farmers. Science Advances, 6(22): eaaz5344, pp. 1-16. doi:10.1126/sciadv.aaz5344.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-7FC3-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0007-77D0-8
Genre: Journal Article

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Supplement (Supplementary material)
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Legends for tables S1 to S17; Table S18; Figs. S1 to S18; Supplementary Text SI1 to SI10; References; Table S1-S5; Table S6-S17. - (last checked: Nov. 2020)

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 Creators:
Rivollat, Maite1, Author              
Jeong, Choongwon1, Author              
Schiffels, Stephan1, Author              
Kücükkalıpcı, İsil, Author
Pemonge, Marie-Hélène, Author
Rohrlach, Adam Ben2, Author              
Alt, Kurt W., Author
Binder, Didier, Author
Friederich, Susanne, Author
Ghesquière, Emmanuel, Author
Gronenborn, Detlef, Author
Laporte, Luc, Author
Lefranc, Philippe, Author
Meller, Harald, Author
Réveillas, Hélène, Author
Rosenstock, Eva, Author
Rottier, Stéphane, Author
Scarre, Chris, Author
Soler, Ludovic, Author
Wahl, Joachim, Author
Krause, Johannes1, Author              Deguilloux, Marie-France, AuthorHaak, Wolfgang1, Author               more..
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              
2PALEoRIDER, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2541702              

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Free keywords: adult,agricultural worker, France, Germany, human experiment, hunter-gatherer, major clinical study, Mesolithic, Neolithic, Western European
 Abstract: Starting from 12,000 years ago in the Middle East, the Neolithic lifestyle spread across Europe via separate continental and Mediterranean routes. Genomes from early European farmers have shown a clear Near Eastern/Anatolian genetic affinity with limited contribution from hunter-gatherers. However, no genomic data are available from modern-day France, where both routes converged, as evidenced by a mosaic cultural pattern. Here, we present genome-wide data from 101 individuals from 12 sites covering today’}s France and Germany from the Mesolithic (N = 3) to the Neolithic (N = 98) (7000{–3000 BCE). Using the genetic substructure observed in European hunter-gatherers, we characterize diverse patterns of admixture in different regions, consistent with both routes of expansion. Early western European farmers show a higher proportion of distinctly western hunter-gatherer ancestry compared to central/southeastern farmers. Our data highlight the complexity of the biological interactions during the Neolithic expansion by revealing major regional variations.

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Language(s): eng - English
 Dates: 2020-05-292020-05-27
 Publication Status: Published in print
 Pages: 17
 Publishing info: -
 Table of Contents: Introduction
Results
- Quantifiying universal HG ancestry in European farmer groups
- Genetic structure in European HG
- Tracing different HG ancestries in farmer groups
- Late survival of HG ancestry in central Europe
- Estamating admixture dates between HG and early farmers
- Tracing GoyetQ2 ancestry in France
- Connections with Britain and Ireland
Discussion
Materials and methods
- Study design
-- Archaeological samples
-- Sampling
-- DNA extraction
-- Library construction
-- Shotgun screening and capture
- aDNA data processing
-- Read processing and aDNA damage
-- Sex determination
-- Contamination estimation
-- Genotyping
-- Mitochondrial and Y chromosome haplogroup assignment
-- Kinship analysis
-- Phenotypic and functional analysis
- Population genetic analysis
-- Merging new dataset wit published data
-- Group leads
-- Principal components analysis
-- f-Statistics
-- qpAdm modeling
-- Admixture data estimation
 Rev. Type: Peer
 Identifiers: DOI: 10.1126/sciadv.aaz5344
ISSN: shh2621
 Degree: -

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Project name : PALEoRIDER
Grant ID : 771234
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)

Source 1

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Title: Science Advances
  Other : Sci. Adv.
Source Genre: Journal
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Publ. Info: Washington : AAAS
Pages: - Volume / Issue: 6 (22) Sequence Number: eaaz5344 Start / End Page: 1 - 16 Identifier: ISSN: 2375-2548
CoNE: https://pure.mpg.de/cone/journals/resource/2375-2548