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  Inhibitors of calmodulin-dependent phosphorylation simultaneously inhibit calcium uptake and calcium-dependent ATPase activity in skeletal muscle sarcoplasmic reticulum and transiently induce calcium release

Hasselbach, W., & Migala, A. (1984). Inhibitors of calmodulin-dependent phosphorylation simultaneously inhibit calcium uptake and calcium-dependent ATPase activity in skeletal muscle sarcoplasmic reticulum and transiently induce calcium release. Zeitschrift für Naturforschung, C: Journal of Biosciences, 39(11-12), 1189-1191. doi:10.1515/znc-1984-11-1235.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0006-8B8F-D Version Permalink: https://hdl.handle.net/21.11116/0000-0006-8B92-8
Genre: Journal Article

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 Creators:
Hasselbach, Wilhelm1, Author           
Migala, Andrea2, Author           
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1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              
2Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              

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 Abstract: Under adequate experimental conditions calmodulin antagonists like compound 48/80 do not dissociate calcium uptake from the calcium-dependent ATP hydrolysis of skeletal muscle sarcoplasmic reticulum membranes but simultaneously inhibit both processes. Apart from the agent's pump inhibiting effect, they interact with the caffeine sensitive calcium channel in the sarcoplasmic reticulum causing a rapid transient calcium release.

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Language(s): eng - English
 Dates: 1984-08-312014-06-021984
 Publication Status: Issued
 Pages: 3
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1515/znc-1984-11-1235
URI: https://pubmed.ncbi.nlm.nih.gov/6241766/
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Title: Zeitschrift für Naturforschung, C: Journal of Biosciences
  Abbreviation : Z. Naturforsch., C: J. Biosci.
Source Genre: Journal
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Publ. Info: Berlin : Walter de Gruyter GmbH
Pages: - Volume / Issue: 39 (11-12) Sequence Number: - Start / End Page: 1189 - 1191 Identifier: ISSN: 1865-7125
CoNE: https://pure.mpg.de/cone/journals/resource/954927655916_1