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  Progress towards artificial hydrolases: synthesis and binding properties of a water-soluble cyclophane host with a phenol cap

Schürmann, G., & Diederich, F. N. (1986). Progress towards artificial hydrolases: synthesis and binding properties of a water-soluble cyclophane host with a phenol cap. Tetrahedron Letters, 27(36), 4249-4252. doi:10.1016/S0040-4039(00)94244-8.

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TetrahedronLett_27_1986_4249.pdf (Any fulltext), 246KB
 
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Schürmann, G.1, Author           
Diederich, Francois Nico1, Author           
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1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              

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 Abstract: The synthesis of the functionalized macrobicyclic host1 on the way to the water-soluble artificial esterase 2 is presented. A phenolic nucleophile is properly oriented atop the binding cavity of1 which forms strong complexes with aromatic guests in aqueous solutions.
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The synthesis of the macrobicyclic host1 on the way to the water-soluble artificial esterase2 is described. Host1 has a phenolic nucleophile atop the binding cavity and complexes aromatic guests in aqueous solution.

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Language(s): eng - English
 Dates: 1986-05-192001-04-021986
 Publication Status: Issued
 Pages: 4
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/S0040-4039(00)94244-8
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Title: Tetrahedron Letters
  Other : Tetrahedron Lett.
Source Genre: Journal
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Publ. Info: Oxford : Pergamon
Pages: - Volume / Issue: 27 (36) Sequence Number: - Start / End Page: 4249 - 4252 Identifier: ISSN: 0040-4039
CoNE: https://pure.mpg.de/cone/journals/resource/954925448772