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  Synthetic cell division via membrane-transforming molecular assemblies

Kretschmer, S., Ganzinger, K., Franquelim, H., & Schwille, P. (2019). Synthetic cell division via membrane-transforming molecular assemblies. BMC Biology, 17: 43. doi:10.1186/s12915-019-0665-1.

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Genre: Journal Article
Subtitle : Review

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Kretschmer et al..pdf (Publisher version), 2MB
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 Creators:
Kretschmer, Simon1, Author              
Ganzinger, Kristina1, Author              
Franquelim, Henri1, Author              
Schwille, Petra1, Author              
Affiliations:
1Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565169              

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 Abstract: Reproduction, i.e. the ability to produce new individuals from a parent organism, is a hallmark of living matter. Even the simplest forms of reproduction require cell division: attempts to create a designer cell therefore should include a synthetic cell division machinery. In this review, we will illustrate how nature solves this task, describing membrane remodelling processes in general and focusing on bacterial cell division in particular. We discuss recent progress made in their in vitro reconstitution, identify open challenges, and suggest how purely synthetic building blocks could provide an additional and attractive route to creating artificial cell division machineries.

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Language(s): eng - English
 Dates: 2019
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1186/s12915-019-0665-1
 Degree: -

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Project name : Marie Skłodowska-Curie grant agreement
Grant ID : 703132
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)
Project name : project A09 of the SFB1032 “Nanoagents for the spatiotemporal control of molecular and cellular reactions”
Grant ID : -
Funding program : -
Funding organization : DFG

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Title: BMC Biology
Source Genre: Journal
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Publ. Info: Springer
Pages: - Volume / Issue: 17 Sequence Number: 43 Start / End Page: - Identifier: ISSN: 1741-7007
CoNE: https://pure.mpg.de/cone/journals/resource/111071069889000