Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Intracellular morphogens: Specifying patterns at the subcellular scale

Hubatsch, L., & Goehring, N. W. (2020). Intracellular morphogens: Specifying patterns at the subcellular scale. In S. Small, & J. Briscoe (Eds.), Gradients and Tissue Patterning (pp. 247-278). Cambridge, MA: Elsevier. doi:10.1016/bs.ctdb.2019.11.006.

Item is

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Hubatsch, Lars1, Autor           
Goehring, Nathan W.2, Autor
Affiliations:
1Max Planck Institute for the Physics of Complex Systems, Max Planck Society, ou_2117288              
2external, ou_persistent22              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 MPIPKS: Structure formation and active systems
 Zusammenfassung: The notion that graded distributions of signals underlie the spatial organization of biological systems has long been a central pillar in the fields of cell and developmental biology. During morphogenesis, morphogens spread across tissues to guide development of the embryo. Similarly, a variety of dynamic gradients and pattern-forming networks have been discovered that shape subcellular organization. Here we discuss the principles of intracellular pattern formation by these intracellular morphogens and relate them to conceptually similar processes operating at the tissue scale. We will specifically review mechanisms for generating cellular asymmetry and consider how intracellular patterning networks are controlled and adapt to cellular geometry. Finally, we assess the general concept of intracellular gradients as a mechanism for positional control in light of current data, highlighting how the simple readout of fixed concentration thresholds fails to fully capture the complexity of spatial patterning processes occurring inside cells.

Details

einblenden:
ausblenden:
Sprache(n):
 Datum: 2019-12-132020
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: ISI: 000532669100009
DOI: 10.1016/bs.ctdb.2019.11.006
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Gradients and Tissue Patterning
Genre der Quelle: Buch
 Urheber:
Small, Stephen1, Herausgeber
Briscoe, James1, Herausgeber
Affiliations:
1 External Organizations, ou_persistent22            
Ort, Verlag, Ausgabe: Cambridge, MA : Elsevier
Seiten: - Band / Heft: - Artikelnummer: - Start- / Endseite: 247 - 278 Identifikator: ISBN: 978-0-12-812791-9; 978-0-12-812790-2

Quelle 2

einblenden:
ausblenden:
Titel: Current Topics in Developmental Biology
Genre der Quelle: Reihe
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Cambridge, MA : Elsevier
Seiten: - Band / Heft: 137 Artikelnummer: - Start- / Endseite: - Identifikator: ISSN: 0070-2153