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  Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study

Oksuzyan, A., Sauer, T., Gampe, J., Höhn, A., Wod, M., Christensen, K., & Wastesson, J. W. (2019). Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study. Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 74(5), 742-747. doi:10.1093/gerona/gly104.

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アイテムのパーマリンク: https://hdl.handle.net/21.11116/0000-0006-B020-E 版のパーマリンク: https://hdl.handle.net/21.11116/0000-0006-B021-D
資料種別: 学術論文

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 作成者:
Oksuzyan, Anna1, 著者
Sauer, Torsten1, 著者
Gampe, Jutta1, 著者
Höhn, Andreas1, 著者
Wod, Mette, 著者
Christensen, Kaare, 著者
Wastesson, Jonas W., 著者
所属:
1Max Planck Institute for Demographic Research, ou_3148316              

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 要旨: Background: This study investigates the accuracy of the reporting of medication use by proxy- and self-respondents, and it compares the prognostic value of the number of medications from survey and registry data for predicting mortality across self- and proxy-respondents. Methods: The study is based on the linkage of the Longitudinal Study of Aging Danish Twins and the Danish 1905–Cohort Study with the Danish National Prescription Registry. We investigated the concordance between survey and registry data, and the prognostic value of medication use when assessed using survey and registry data, to predict mortality for self- and proxy-respondents at intake surveys. Results: Among self-respondents, the agreement was moderate (κ = 0.52–0.58) for most therapeutic groups, whereas among proxy-respondents, the agreement was low to moderate (κ = 0.36–0.60). The magnitude of the relative differences was, generally, greater among proxies than among self-respondents. Each additional increase in the total number of medications was associated with 7%–8% mortality increase among self- and 4%–6% mortality increase among proxy-respondents in both the survey and registry data. The predictive value of the total number of medications estimated from either data source was lower among proxies (c-statistic = 0.56–0.58) than among self-respondents (c-statistic = 0.74). Conclusions: The concordance between survey and registry data regarding medication use and the predictive value of the number of medications for mortality were lower among proxy- than among self-respondents.

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 日付: 2019
 出版の状態: 出版
 ページ: -
 出版情報: -
 目次: -
 査読: 査読あり
 識別子（DOI, ISBNなど）: その他: 6048
DOI: 10.1093/gerona/gly104
 学位: -

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出版物 1

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出版物名: Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
種別: 学術雑誌
 著者・編者:
所属:
出版社, 出版地: -
ページ: - 巻号: 74 (5) 通巻号: - 開始・終了ページ: 742 - 747 識別子（ISBN, ISSN, DOIなど）: -