English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study

Oksuzyan, A., Sauer, T., Gampe, J., Höhn, A., Wod, M., Christensen, K., et al. (2019). Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study. Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 74(5), 742-747. doi:10.1093/gerona/gly104.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-0006-B020-E Version Permalink: https://hdl.handle.net/21.11116/0000-0006-B021-D
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Oksuzyan, Anna1, Author
Sauer, Torsten1, Author
Gampe, Jutta1, Author
Höhn, Andreas1, Author
Wod, Mette, Author
Christensen, Kaare, Author
Wastesson, Jonas W., Author
Affiliations:
1Max Planck Institute for Demographic Research, ou_3148316              

Content

show
hide
Free keywords: -
 Abstract: Background: This study investigates the accuracy of the reporting of medication use by proxy- and self-respondents, and it compares the prognostic value of the number of medications from survey and registry data for predicting mortality across self- and proxy-respondents. Methods: The study is based on the linkage of the Longitudinal Study of Aging Danish Twins and the Danish 1905–Cohort Study with the Danish National Prescription Registry. We investigated the concordance between survey and registry data, and the prognostic value of medication use when assessed using survey and registry data, to predict mortality for self- and proxy-respondents at intake surveys. Results: Among self-respondents, the agreement was moderate (κ = 0.52–0.58) for most therapeutic groups, whereas among proxy-respondents, the agreement was low to moderate (κ = 0.36–0.60). The magnitude of the relative differences was, generally, greater among proxies than among self-respondents. Each additional increase in the total number of medications was associated with 7%–8% mortality increase among self- and 4%–6% mortality increase among proxy-respondents in both the survey and registry data. The predictive value of the total number of medications estimated from either data source was lower among proxies (c-statistic = 0.56–0.58) than among self-respondents (c-statistic = 0.74). Conclusions: The concordance between survey and registry data regarding medication use and the predictive value of the number of medications for mortality were lower among proxy- than among self-respondents.

Details

show
hide
Language(s):
 Dates: 2019
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: Other: 6048
DOI: 10.1093/gerona/gly104
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 74 (5) Sequence Number: - Start / End Page: 742 - 747 Identifier: -