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  The use of yttrium in medical imaging and therapy: historical background and future perspectives

Tickner, B., Stasiuk, G., Duckett, S., & Angelovski, G. (2020). The use of yttrium in medical imaging and therapy: historical background and future perspectives. Chemical Society Reviews, 49(17), 6169-6185. doi:10.1039/c9cs00840c.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-C2DE-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-F9CF-9
Genre: Journal Article

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 Creators:
Tickner, BJ, Author
Stasiuk, GJ, Author
Duckett, SB, Author
Angelovski, G1, 2, Author              
Affiliations:
1Research Group MR Neuroimaging Agents, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528691              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Yttrium is a chemically versatile rare earth element that finds use in a range of applications including lasers and superconductors. In medicine, yttrium-based materials are used in medical lasers and biomedical implants. This is extended through the array of available yttrium isotopes to enable roles for 90Y complexes as radiopharmaceuticals and 86Y tracers for positron emission tomography (PET) imaging. The naturally abundant isotope 89Y is proving to be suitable for nuclear magnetic resonance investigations, where initial reports in the emerging field of hyperpolarised magnetic resonance imaging (MRI) are promising. In this review we explore the coordination and radiochemical properties of yttrium, and its role in drugs for radiotherapy, PET imaging agents and perspectives for applications in hyperpolarised MRI.

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 Dates: 2020-072020-09
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1039/c9cs00840c
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Title: Chemical Society Reviews
  Other : Chem. Soc. Rev.
Source Genre: Journal
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Publ. Info: London : Royal Society of Chemistry, etc.
Pages: - Volume / Issue: 49 (17) Sequence Number: - Start / End Page: 6169 - 6185 Identifier: ISSN: 0306-0012
CoNE: https://pure.mpg.de/cone/journals/resource/110992357259182