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  Relaxometry differences between magno- and parvocellular human LGN subdivisions revealed by in- and ex-vivo quantitative MRI

Müller-Axt, C., Eichner, C., Kauffmann, L., Bazin, P.-L., Rusch, H., Morawski, M., et al. (2020). Relaxometry differences between magno- and parvocellular human LGN subdivisions revealed by in- and ex-vivo quantitative MRI. In Proceedings of the 28th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM).

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 Creators:
Müller-Axt, Christa1, Author           
Eichner, Cornelius2, Author           
Kauffmann, Louise, Author
Bazin, Pierre-Louis3, Author           
Rusch, Henriette, Author
Morawski, Markus3, Author           
Anwander, Alfred2, Author           
von Kriegstein, Katharina1, Author           
Affiliations:
1Max Planck Research Group Neural Mechanisms of Human Communication, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634556              
2Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551              
3Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              

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 Abstract: The human lateral geniculate nucleus (LGN) is the central station for visual processing before information reaches the cerebral cortex. It is characterized by subdivisions with distinct cyto- and myeloarchitecture. Due to its small size, imaging of the LGN and especially its subdivisions is challenging. Here, we show that the LGN and its subdivisions can be identified using in-vivo and ex-vivo high-field quantitative MRI with ultra-high resolution. We present the to-date first atlas of the LGN and its estimated subdivisions. This work will serve as a highly valuable tool both for neuroscientists and clinicians investigating the visual system and its disorders.

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 Dates: 2020-08-08
 Publication Status: Published online
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Title: Proceedings of the 28th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Source Genre: Proceedings
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Pages: - Volume / Issue: 28 Sequence Number: 3153 Start / End Page: - Identifier: -