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  Improving safety of MRI in patients with deep brain stimulation devices

Boutet, A., Chow, C. T., Narang, K., Elias, G. J. B., Neudorfer, C., Germann, J., et al. (2020). Improving safety of MRI in patients with deep brain stimulation devices. Radiology, 296(2), 250-262. doi:10.1148/radiol.2020192291.

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Boutet, Alexandre1, 2, Autor
Chow, Clement T.1, Autor
Narang, Keshav1, Autor
Elias, Gavin J. B.1, Autor
Neudorfer, Clemens1, Autor
Germann, Jürgen1, Autor
Ranjan, Manish3, 4, Autor
Loh, Aaron1, Autor
Martin, Alastair J.5, Autor
Kucharczyk, Walter1, 2, Autor
Steele, Christopher6, 7, Autor           
Hancu, Ileana8, Autor
Rezai, Ali R.3, 4, Autor
Lozano, Andres M.1, 9, Autor
Affiliations:
1University Health Network, University of Toronto, ON, Canada, ou_persistent22              
2Joint Department of Medical Imaging, University of Toronto, ON, Canada, ou_persistent22              
3Department of Neurosurgery, West Virginia University, Morgantown, WV, USA, ou_persistent22              
4Department of Neurosurgery, Rockefeller Neuroscience Institute, Morgantown, WV, USA, ou_persistent22              
5Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA, ou_persistent22              
6Department of Psychology, Concordia University, Montréal, QC, Canada, ou_persistent22              
7Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
8Center for Scientific Review, National Institutes of Health, Bethesda, MD, USA, ou_persistent22              
9Department of Surgery, University of Toronto, ON, Canada, ou_persistent22              

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 Zusammenfassung: MRI is a valuable clinical and research tool for patients undergoing deep brain stimulation (DBS). However, risks associated with imaging DBS devices have led to stringent regulations, limiting the clinical and research utility of MRI in these patients. The main risks in patients with DBS devices undergoing MRI are heating at the electrode tips, induced currents, implantable pulse generator dysfunction, and mechanical forces. Phantom model studies indicate that electrode tip heating remains the most serious risk for modern DBS devices. The absence of adverse events in patients imaged under DBS vendor guidelines for MRI demonstrates the general safety of MRI for patients with DBS devices. Moreover, recent work indicates that-given adequate safety data-patients may be imaged outside these guidelines. At present, investigators are primarily focused on improving DBS device and MRI safety through the development of tools, including safety simulation models. Existing guidelines provide a standardized framework for performing safe MRI in patients with DBS devices. It also highlights the possibility of expanding MRI as a tool for research and clinical care in these patients going forward.

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Sprache(n): eng - English
 Datum: 2020-06-232020-08
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1148/radiol.2020192291
PMID: 32573388
 Art des Abschluß: -

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Titel: Radiology
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Easton, Pa., etc. : Radiological Society of North America.
Seiten: - Band / Heft: 296 (2) Artikelnummer: - Start- / Endseite: 250 - 262 Identifikator: ISSN: 0033-8419
CoNE: https://pure.mpg.de/cone/journals/resource/954925437502