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  The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database

Alkemade, A., Mulder, M. J., Groot, J. M., Isaacs, B. R., van Berendonk, N., Lute, N., et al. (2020). The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database. NeuroImage, 221: 117200. doi:10.1016/j.neuroimage.2020.117200.

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 Creators:
Alkemade, Anneke1, Author
Mulder, Martijn J.1, 2, Author
Groot, Josephine M.1, Author
Isaacs, Bethany R.1, 3, Author
van Berendonk, Nikita1, Author
Lute, Nicky1, 4, Author
Isherwood, Scott J. S.1, Author
Bazin, Pierre-Louis1, 5, Author              
Forstmann, Birte U.1, Author
Affiliations:
1Integrative Model-Based Cognitive Neuroscience Research Unit (IMCN), University of Amsterdam, the Netherlands, ou_persistent22              
2Department of Psychology, Utrecht University, the Netherlands, ou_persistent22              
3Department of Neurosurgery, Maastricht University, the Netherlands, ou_persistent22              
4Section Clinical Neuropsychology, VU University Amsterdam, the Netherlands, ou_persistent22              
5Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              

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Free keywords: Ultra-high field 7 Tesla structural MRI; Subcortex; Probabilistic maps; Basal ganglia
 Abstract: Normative databases allow testing of novel hypotheses without the costly collection of magnetic resonance imaging (MRI) data. Here we present the Amsterdam Ultra-high field adult lifespan database (AHEAD). The AHEAD consists of 105 7 Tesla (T) whole-brain structural MRI scans tailored specifically to imaging of the human subcortex, including both male and female participants and covering the entire adult life span (18–80 yrs). We used these data to create probability maps for the subthalamic nucleus, substantia nigra, internal and external segment of the globus pallidus, and the red nucleus. Data was acquired at a submillimeter resolution using a multi-echo (ME) extension of the second gradient-echo image of the MP2RAGE sequence (MP2RAGEME) sequence, resulting in complete anatomical alignment of quantitative, R1-maps, R2*-maps, T1-maps, T1-weighted images, T2*-maps, and quantitative susceptibility mapping (QSM). Quantitative MRI maps, and derived probability maps of basal ganglia structures are freely available for further analyses.

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Language(s): eng - English
 Dates: 2020-07-012020-07-222020-08-012020-11-01
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.neuroimage.2020.117200
Other: online ahead of print
PMID: 32745682
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Title: NeuroImage
Source Genre: Journal
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Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 221 Sequence Number: 117200 Start / End Page: - Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166