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  Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields

Pérez-Rodas, M., Schulz, H., Pohmann, R., Scheffler, K., & Heule, R. (2020). Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0006-D873-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0006-E7CF-D
Genre: Poster

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Pérez-Rodas, M1, 2, Author              
Schulz, H1, 2, Author              
Pohmann, R1, 2, Author              
Scheffler, K1, 2, Author              
Heule, R1, 2, Author              
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1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: To fully understand the neurovascular fingerprint observed in BOLD experiments, extravascular and intravascular contributions have to be identified separately. Balanced steady-state free precession (bSSFP) imaging has demonstrated the ability for distortion-free fMRI with high microvascular sensitivity. However, the underlying intravascular contribution to BOLD bSSFP is not yet entirely known as literature R2 relaxation rates do not reflect the apparent diffusion-related R2 decrease in blood with shorter bSSFP refocusing intervals (TRs). This work thus focuses on characterizing the oxygen sensitivity of bSSFP in blood samples at high to ultra-high fields by means of passband signal differences and intrinsic R2 estimation.

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 Dates: 2020-08
 Publication Status: Published online
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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
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Start-/End Date: 2020-08-08 - 2020-08-14

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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1117 Start / End Page: 415 Identifier: -