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  Functional line-scanning in humans with ultra-high spatiotemporal resolution: reconstruction and BOLD sensitivity assessment

Raimondo, L., Knapen, T., de Oliveira, I., Yu, X., Dumoulin, S., van der Zwaag, W., et al. (2020). Functional line-scanning in humans with ultra-high spatiotemporal resolution: reconstruction and BOLD sensitivity assessment. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.

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Raimondo, L, Author
Knapen, T, Author
de Oliveira, IAF, Author
Yu, X1, 2, Author           
Dumoulin, SO, Author
van der Zwaag, W, Author
Siero, JCW, Author
Affiliations:
1Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528695              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: We present initial results of line-scanning fMRI in humans. The potential of this technique lies in the combination of both high spatial and temporal resolution while sacrificing spatial coverage outside the region of interest. We reached a 250 μm resolution along the line direction with a temporal resolution of 200 ms. Coil sensitivity profiles and the average tSNR per channel were used to optimize the line reconstructions. We obtained similar BOLD sensitivity compared to standard 2D GE-EPI BOLD and high spatial specificity for a visual task. Hence, we demonstrate the feasibility of ultra-high spatiotemporal resolution in humans using line-scanning.

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 Dates: 2020-08
 Publication Status: Published online
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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
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Start-/End Date: 2020-08-08 - 2020-08-14

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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3876 Start / End Page: - Identifier: -