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  Snapshot whole brain CEST MRI at 3T with 3D-EPI

Mueller, S., Stirnberg, R., Akbey, S., Ehses, P., Scheffler, K., Stöcker, T., et al. (2020). Snapshot whole brain CEST MRI at 3T with 3D-EPI. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.

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 Creators:
Mueller, S1, 2, Author              
Stirnberg, R, Author
Akbey, S, Author
Ehses, P, Author              
Scheffler, K1, 2, Author              
Stöcker, T, Author
Zaiss, M1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: CEST MRI provides metabolite-based contrasts but often suffers from poor volume coverage or spatial resolution. We optimized and included a snapshot 3D-EPI readout and propose a suitable post-processing pipeline to generate CEST contrast in the whole brain at clinical B0=3T. It is shown that CEST MRI with 1.8mm isotropic nominal resolution at a field of view of 256x224x156mm³ is feasible within 4.3s per presaturation frequency offset. The approach is adaptable for any presaturation scheme. Exemplarily low power saturation was performed and fitted Lorentzian amplitudes gave a coefficient of variation <8.5% across three healthy subjects.

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 Dates: 2020-08
 Publication Status: Published online
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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
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Start-/End Date: 2020-08-08 - 2020-08-14

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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3096 Start / End Page: - Identifier: -