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  Acquisition-weighted MR Current Density Imaging (AW-MRCDI) improves sensitivity and spatial resolution

Göksu, C., Hanson, L., Gregersen, F., Scheffler, K., & Thielscher, A. (2020). Acquisition-weighted MR Current Density Imaging (AW-MRCDI) improves sensitivity and spatial resolution. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.

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Göksu, C, Author              
Hanson, LG, Author
Gregersen, F, Author
Scheffler, K1, 2, Author              
Thielscher, A, Author              
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Exact knowledge of currents flowing inside the human brain is important for several neuroscientific applications. MRCDI combines MR with externally injected weak currents, and uses measurements of the current-induced magnetic field to estimate spatial current distribution. The method’s accuracy highly depends on the sensitivity and spatial resolution of the field measurements. Here, we improve the currently most sensitive MRCDI method based on steady-state free precession free induction decay (SSFP-FID) by using an acquisition-weighted scheme (AW-MRCDI). We compared weighted and conventional schemes by phantom experiments. AW-MRCDI demonstrated 59% increase in sensitivity and significantly improved the spatial resolution.

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 Dates: 2020-08
 Publication Status: Published online
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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
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Start-/End Date: 2020-08-08 - 2020-08-14

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Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3189 Start / End Page: - Identifier: -