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  Recent advances and future challenges in glycan microarray technology

de Paz, J. L., & Seeberger, P. H. (2012). Recent advances and future challenges in glycan microarray technology. In Methods in Molecular Biology (pp. 1-12). Totowa, NJ: Humana Press.

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Chapter.pdf (Publisher version), 313KB
 
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 Creators:
de Paz, José L., Author
Seeberger, Peter H.1, Author              
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1Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2040285              

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 Abstract: Glycan microarrays, carrying hundreds of different sugars on chip surfaces, have become a standard tool for the study of interactions of biomolecules with carbohydrates. The chip-based format offers important advantages, including the ability to screen in parallel several thousand binding events on a single slide, the minimal amount of sample required for one experiment, and the multivalent display of sugars on the chip that mimics the presentation of carbohydrates in nature. This chapter presents recent advances and future challenges in glycan microarray technology. We describe different immobilization and detection methods as well as applications in glycomics, drug discovery, and biomedicine.

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Language(s): eng - English
 Dates: 2012
 Publication Status: Published in print
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 Identifiers: DOI: 10.1007/978-1-61779-373-8_1
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Title: Methods in Molecular Biology
  Other : Methods Mol. Biol.
Source Genre: Journal
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Publ. Info: Totowa, NJ : Humana Press
Pages: - Volume / Issue: 808 Sequence Number: - Start / End Page: 1 - 12 Identifier: ISSN: 1064-3745

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Title: Carbohydrate Microarrays: Methods and Protocols
Source Genre: Book
 Creator(s):
Chevolot, Yann, Editor
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Publ. Info: Totowa, NJ : Humana Press
Pages: 427 S. Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: ISBN: 978-1-61779-373-8